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New method for efficient control of hydrogen sulfide and methane in gravity sewers: Combination of NaOH

《环境科学与工程前沿（英文）》 2022年 第16卷 第6期 doi: 10.1007/s11783-021-1509-0

摘要：

• The combination of NaOH and nitrite was used to control harmful gas in sewers.

关键词： Sewer corrosion     Sulfide control     Combination treatment     NaOH     Nitrite    

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Level set band method: A combination of density-based and level set methods for the topology optimization

Peng WEI, Wenwen WANG, Yang YANG, Michael Yu WANG

《机械工程前沿（英文）》 2020年 第15卷 第3期   页码 390-405 doi: 10.1007/s11465-020-0588-0

摘要： The level set method (LSM), which is transplanted from the computer graphics field, has been successfully introduced into the structural topology optimization field for about two decades, but it still has not been widely applied to practical engineering problems as density-based methods do. One of the reasons is that it acts as a boundary evolution algorithm, which is not as flexible as density-based methods at controlling topology changes. In this study, a level set band method is proposed to overcome this drawback in handling topology changes in the level set framework. This scheme is proposed to improve the continuity of objective and constraint functions by incorporating one parameter, namely, level set band, to seamlessly combine LSM and density-based method to utilize their advantages. The proposed method demonstrates a flexible topology change by applying a certain size of the level set band and can converge to a clear boundary representation methodology. The method is easy to implement for improving existing LSMs and does not require the introduction of penalization or filtering factors that are prone to numerical issues. Several 2D and 3D numerical examples of compliance minimization problems are studied to illustrate the effects of the proposed method.

关键词： level set method     topology optimization     density-based method     level set band    

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A combination of damage locating vector method (DLV) and differential evolution algorithm (DE) for structural

T. NGUYEN-THOI, A. TRAN-VIET, N. NGUYEN-MINH, T. VO-DUY, V. HO-HUU

《结构与土木工程前沿（英文）》 2018年 第12卷 第1期   页码 92-108 doi: 10.1007/s11709-016-0379-1

摘要： In this study, a two-stage method is presented for identifying multiple damage scenarios. In the first stage, the damage locating vector (DLV) method using normalized cumulative energy ( ) is employed for damage localization in structures. In the second stage, the differential evolution algorithm (DE) is used for damage severity of the structures. In addition, in the second stage, a modification of an available objective function is made for handing the issue of symmetric structures. To verify the effectiveness of the present technique, numerical examples of a 72-bar space truss and a one-span steel portal frame are considered. In addition, the effect of noise on the performance of the identification results is also investigated. The numerical results show that the proposed combination gives good assessment of damage location and extent for multiple structural damage cases.

关键词： damage assessment     damage locating vector method (DLV)     differential evolution (DE)     multiple damage location assurance criterion (MDLAC)     mode shape error function    

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Stability analysis of a high loess slope reinforced by the combination system of soil nails and stabilization

Jiu-jiang WU,Qian-gong CHENG,Xin LIANG,Jian-Lei CAO

《结构与土木工程前沿（英文）》 2014年 第8卷 第3期   页码 252-259 doi: 10.1007/s11709-014-0260-z

摘要： While the soil nails and the corresponding compound technology are widely used as the support techniques for deep foundation pit and normal slopes, few related engineering cases are found for high loess slopes. By utilizing the finite element software of PLAXIS 8.5, the behavior of a high loess slope reinforced by the combination of soil nails and stabilization piles (hereinafter for CSNSP) is studied in this paper. It can be found that the potential slide surface of the slope moves to deeper locations during the process of the multi-staged excavations. The measure of reducing the weight of the top of the slope is a positive factor to the stability of the loess slope, while the rainfall is a negative factor. The slope can’t be stable if it’s reinforced only by stabilization piles or soil nails during the process of the multi-staged excavations. The soil nail contributes greater to the overall system stability when the excavation depth is relatively shallow, while the stabilization pile takes it over when the excavation depth reaches a large value. Compared to the results from the Sweden circular slip surface, the data derived from the method of phi/c reduction is relatively large when the slope is unreinforced or reinforced only by stabilization pile, and the data turns to be small when the slope is strengthened by soil nails or the combination system of soil nails and stabilization piles.

关键词： high loess slope     CSNSP     PLAXIS     phi/c strength reduction method     Sweden circular slip surface    

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Immunotherapy-based combination strategies for treatment of gastrointestinal cancers: current status

Chenfei Zhou, Jun Zhang

《医学前沿（英文）》 2019年 第13卷 第1期   页码 12-23 doi: 10.1007/s11684-019-0685-9

摘要：

Strategies in comprehensive therapy for gastrointestinal (GI) cancer have been optimized in the last decades to improve patients’ outcomes. However, treatment options remain limited for late-stage or refractory diseases. The efficacy of immune checkpoint inhibitors (ICIs) for treatment of refractory GI cancer has been confirmed by randomized clinical trials. In 2017, pembrolizumab was approved by the US Food and Drug Administration as the first agent for treatment of metastatic solid tumors with mismatch repair deficiency, especially for colorectal cancer. Given the different mechanisms, oncologists have focused on determining whether ICIs-based combination strategies could achieve higher efficacy than conventional therapy alone in late-stage or even front-line treatment of GI cancer. This review discusses the current status of combining immune checkpoint inhibitors with molecular targeted therapy, chemotherapy, or radiotherapy in GI cancer in terms of mechanisms, safety, and efficacy to provide basis for future research.

关键词： gastrointestinal cancer     immune checkpoint inhibitor     combination therapy    

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Conceptual design of compliant translational joints for high-precision applications

Guangbo HAO,Haiyang LI,Xiuyun HE,Xianwen KONG

《机械工程前沿（英文）》 2014年 第9卷 第4期   页码 331-343 doi: 10.1007/s11465-014-0321-y

摘要：

Compliant translational joints (CTJs) have been extensively used in precision engineering and microelectromechanical systems (MEMS). There is an increasing need for designing higher-performance CTJs. This paper deals with the conceptual design of CTJs via three approaches: parallelogram based method, straight-line motion mechanism based method and combination based method. Typical emerging CTJ designs are reviewed by explaining their design principles and qualitatively analyzing their characteristics. New CTJs are proposed using three approaches, including an asymmetric double parallelogram mechanism with slaving mechanism, several compact and symmetric double parallelogram mechanisms with slaving mechanisms and a general CTJ using the center drift compensation and a CTJ using Roberts linkage and several combination designs. This paper provides an overview of the current advances/progresses of CTJ designs and lays the foundation for further optimization, quantitative analysis and characteristic comparisons.

关键词： compliant mechanisms     translational joints     conceptual design     parallelogram     straight-line motion     combination method    

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汶川巨震的预测和思考

耿庆国

《中国工程科学》 2009年 第11卷 第6期   页码 123-128

摘要：

根据多年来对旱震关系、强震活动有序性及强磁暴组合法的地震预测探索，就川、甘、青、陕，特别是四川阿坝州地区的地震活动连续3年的研究做了简要的回顾，披露了在汶川地震前的２００５ 年１２ 月８ 日向中国地震局提交的“关于加强川甘青交界地区强震短临监测和分析预报应急工作的紧急建议”要点。

关键词： 汶川巨震预测     旱震关系     强震活动有序性     强磁暴组合法    

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Removal of virus aerosols by the combination of filtration and UV-C irradiation

《环境科学与工程前沿（英文）》 2023年 第17卷 第3期 doi: 10.1007/s11783-023-1627-y

摘要：

● The removal of virus aerosols by filtration and UV-C irradiation was proposed.

关键词： Filtration system     UV-C irradiation     Virus aerosol     Public health     COVID-19    

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基于评价方法属性层次的组合评价研究

陈衍泰,陈国宏,李美娟

《中国工程科学》 2005年 第7卷 第8期   页码 56-59

摘要：

针对现存的多种单一综合评价方法机理、属性层次相异引起的对同一个对象评价结论不相容的问题，提出一种新的组合评价方法。定义了“具有相容性”与“特殊属性”的两类综合评价方法；建立了两个组合评价模型，分别将这两个属性层次方法所得的不一致的评价值与排序结论进行组合；在此基础上提出“复组合”的概念。并应用此模型对我国欠发达地区15个城市的综合实力进行评价，使得系统评价更具有科学性和实用性，为欠发达地区开发战略制订宏观经济政策提供实证基础。

关键词： 评价方法的属性层次     组合模型     复组合    

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Research on Evaluating the Efficiency of the Project Financing of the Energy Service Company

Bao-zhen Zhang,Han-ding Guo,Cai-xia Yang,Lei Wang

《工程管理前沿（英文）》 2016年 第3卷 第3期   页码 252-257 doi: 10.15302/J-FEM-2016044

摘要： The financing efficiency evaluation of the ESCO (Energy Service Company) is an important approach to improve the operation efficiency of existing building energy-saving projects. To scientifically and reasonably evaluate the financing efficiency of the ESCO, this paper puts forward a combination evaluation model based on the method set. Firstly, the method set is composed of different methods that meet the demand of statistical coherence, and KENALL-W coefficient test of concordance is used to check up the coherence of the ranking results of the different methods. Secondly, mean, Borda and Copeland are used separately for calculating the combination evaluation results and the circular combination method is used to ensure the coherence of evaluation results. Finally, the combination evaluation model is used to evaluate the 10 ESCO business project financing benefits, and the effectiveness of the models is verified accordingly.

关键词： ESCO     project financing     financing efficiency     method set     combination evaluation    

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Adsorption in combination with ozonation for the treatment of textile waste water: a critical review

Shraddha Khamparia,Dipika Kaur Jaspal

《环境科学与工程前沿（英文）》 2017年 第11卷 第1期 doi: 10.1007/s11783-017-0899-5

摘要： A combination of adsorption with ozonation proved best for dye removal. Toxicity of the textile effluents can be remarkably reduced by combined method. Wide scope for choice of natural materials for treatment of textile dyes. Intrusion of synthetic textile dyes in the ecosystem has been recognized as a serious issue worldwide. The effluents generated from textiles contain large amount of recalcitrant unfixed dyes which are regarded as emerging contaminants in the field of waste water study. Removal of various toxic dyes often includes diverse and complex set of physico-chemical, biological and advanced oxidation processes adopted for treatment. Adsorption in itself is a well-known technique utilized for treatment of textile effluents using a variety of adsorbents. In addition, ozonation deals with effective removal of dyes using high oxidising power of ozone. The review summarizes dye removal study by a combination of ozonation and adsorption methods. Also, to acquire an effective interpretation of this combined approach of treating wastewater, a thorough study has been made which is deliberated here. Results asserts that, with the combined ability of ozone and a catalyst/adsorbent, there is high possibility of total elimination of dyes from waste water. Several synthetically prepared materials have been used along with few natural materials during the combined treatment. However, considering practical applicability, some areas were identified during the study where work needs to be done for effective implementation of the combined treatment.

关键词： Adsorption     Ozonation     Catalytic Ozonation     Textile dyes     Mineralization    

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Silica-based nanoarchitecture for an optimal combination of photothermal and chemodynamic therapy functions

《化学科学与工程前沿（英文）》 2023年 第17卷 第12期   页码 2144-2155 doi: 10.1007/s11705-023-2362-4

摘要： This study introduces multifunctional silica nanoparticles that exhibit both high photothermal and chemodynamic therapeutic activities, in addition to luminescence. The activity of the silica nanoparticles is derived from their plasmonic properties, which are a result of infusing the silica nanoparticles with multiple Cu2–xS cores. This infusion process is facilitated by a recoating of the silica nanoparticles with a cationic surfactant. The key factors that enable the internal incorporation of the Cu2–xS cores and the external deposition of red-emitting carbon dots are identified. The Cu2–xS cores within the silica nanoparticles exhibit both self-boosting generation of reactive oxygen species and high photothermal conversion efficacy, which are essential for photothermal and chemodynamic activities. The silica nanoparticles’ small size (no more than 70 nm) and high colloidal stability are prerequisites for their cell internalization. The internalization of the red-emitting silica nanoparticles within cells is visualized using fluorescence microscopy techniques. The chemodynamic activity of the silica nanoparticles is associated with their dark cytotoxicity, and the mechanisms of cell death are evaluated using an apoptotic assay. The photothermal activity of the silica nanoparticles is demonstrated by significant cell death under near-infrared (1064 nm) irradiation.

关键词： copper sulfide nanoparticles     chemodynamic therapy     photothermal therapy     carbon dots     silica nanoparticles    

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approach of low carbon and efficient utilization of coal resources: The polygeneration system of a combination

Kechang XIE, Fan LI

《化学科学与工程前沿（英文）》 2010年 第4卷 第4期   页码 383-384 doi: 10.1007/s11705-010-0526-5

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Celecoxib in combination with retinoid CD437 inhibits melanoma A375 cell

Jianwen REN, Zhenhui PENG, Birong GUO, Min PAN

《医学前沿（英文）》 2009年 第3卷 第1期   页码 108-112 doi: 10.1007/s11684-009-0015-8

摘要： This study aimed to investigate the effects of celecoxib, synthetic retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid (CD437) and the combination of the two on cell proliferation, apoptosis, and cycle arrest of human malignant melanoma A375 cells. 3-(4,5-dimethylthiazol-2-yl)-2,5-di-phenyltetrazoliumbromide assay (MTT assay) was applied to determine the anti-proliferative effects of the drugs on human malignant melanoma A375 cells. Flow cytometry was performed to investigate the influence of the drugs on cell cycle and cell apoptosis. Both celecoxib and CD437 could inhibit the growth of human malignant melanoma A375 cells in a dose-dependent manner. Celecoxib at 80 μmol/L inhibited proliferation, induced apoptosis and G /M cell cycle arrest of human malignant melanoma A375 cells after treatment for 24 h [proliferation inhibiting rate: (50.2±2.51)%, apoptosis rate: (35.91±1.80)%]. CD437 at 10 μmol/L inhibited proliferation, induced apoptosis and G /G cell cycle arrest of human malignant melanoma A375 cells after treatment for 24 h [proliferation inhibiting rate: (58.6±2.38)%, apoptosis rate: (28.03±0.77)%]. Celecoxib in combination with CD437 could significantly enhance the effects of inhibiting proliferation and inducing apoptosis of human malignant melanoma A375 cells 24 h after treatment compared with the drug alone [proliferation inhibiting rate: (68.92±1.72)%, apoptosis rate: (42.09±1.05)%, both <0.05] and could decrease the proportion of the S phase in the cell cycle. Celecoxib could inhibit the growth of human malignant melanoma A375 cells by inducing apoptosis and G /M cycle arrest. CD437 could inhibit the growth of human malignant melanoma A375 cells by inducing apoptosis and G /G cycle arrest. Celecoxib exhibited additive effects with CD437 on retarding the growth and inducing apoptosis of human malignant melanoma A375 cells. Celecoxib in combination with CD437 may become an effective method for prevention and treatment of human melanoma.

关键词： celecoxib     CD437     melanoma A375 cell     apoptosis     cycle arrest    

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Combination form analysis and experimental study of mechanical properties on steel sheet glass fiber

《结构与土木工程前沿（英文）》 2021年 第15卷 第4期   页码 834-850 doi: 10.1007/s11709-021-0743-7

摘要： The concept of steel sheet glass fiber reinforced polymer (GFRP) composite bar (SSGCB) was put forward. An optimization plan was proposed in the combined form of SSGCB. The composite principle, material selection, and SSGCB preparation technology have been described in detail. Three-dimensional finite element analysis was adopted to perform the combination form optimization of different steel core structures and different steel core contents based on the mechanical properties. Mechanical tests such as uniaxial tensile, shear, and compressive tests were carried out on SSGCB. Parametric analysis was conducted to investigate the influence of steel content on the mechanical properties of SSGCB. The results revealed that the elastic modulus of SSGCB had improvements and increased with the rise of steel content. Shear strength was also increased with the addition of steel content. Furthermore, the yield state of SSGCB was similar to the steel bar, both of which indicated a multi-stage yield phenomenon. The compressive strength of SSGCB was lower than that of GFRP bars and increased with the increase of the steel core content. Stress-strain curves of SSGCB demonstrated that the nonlinear-stage characteristics of SSGCB-8 were much more obvious than other bars.

关键词： steel sheet GFRP composite bar     combination form     numerical modeling     mechanical properties test     strength    

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标题 作者 时间 类型 操作

New method for efficient control of hydrogen sulfide and methane in gravity sewers: Combination of NaOH

期刊论文

Level set band method: A combination of density-based and level set methods for the topology optimization

Peng WEI, Wenwen WANG, Yang YANG, Michael Yu WANG

期刊论文

A combination of damage locating vector method (DLV) and differential evolution algorithm (DE) for structural

T. NGUYEN-THOI, A. TRAN-VIET, N. NGUYEN-MINH, T. VO-DUY, V. HO-HUU

期刊论文

Stability analysis of a high loess slope reinforced by the combination system of soil nails and stabilization

Jiu-jiang WU,Qian-gong CHENG,Xin LIANG,Jian-Lei CAO

期刊论文

Immunotherapy-based combination strategies for treatment of gastrointestinal cancers: current status

Chenfei Zhou, Jun Zhang

期刊论文

Conceptual design of compliant translational joints for high-precision applications

Guangbo HAO,Haiyang LI,Xiuyun HE,Xianwen KONG

期刊论文

汶川巨震的预测和思考

耿庆国

期刊论文

Removal of virus aerosols by the combination of filtration and UV-C irradiation

期刊论文

基于评价方法属性层次的组合评价研究

陈衍泰,陈国宏,李美娟

期刊论文

Research on Evaluating the Efficiency of the Project Financing of the Energy Service Company

Bao-zhen Zhang,Han-ding Guo,Cai-xia Yang,Lei Wang

期刊论文

Adsorption in combination with ozonation for the treatment of textile waste water: a critical review

Shraddha Khamparia,Dipika Kaur Jaspal

期刊论文

Silica-based nanoarchitecture for an optimal combination of photothermal and chemodynamic therapy functions

期刊论文

approach of low carbon and efficient utilization of coal resources: The polygeneration system of a combination

Kechang XIE, Fan LI

期刊论文

Celecoxib in combination with retinoid CD437 inhibits melanoma A375 cell

Jianwen REN, Zhenhui PENG, Birong GUO, Min PAN

期刊论文

Combination form analysis and experimental study of mechanical properties on steel sheet glass fiber

期刊论文